A method for the production of temperature-sensitive, is not pathogenic mutants of herpes simplex type 2 - viruses and their use for the production of vaccines

摘要

The invention pertains to the preparation of temperature-sensitive and substantially non-pathogenic mutant strains of Herpes Simplex type 2 virus which are valuable for the preparation of vaccines, to the vaccines containing said temperature-sensitive mutant strains and to a new vaccination method against viral exanthermatous diseases.