dihydroxycyclopentano 7.8 - (s) - n - substituees tetrahydroisoquinoleine 1,2,3,4 - and their ethers and esters

摘要

N-substituted cyclopentano[f]-1,2,3,4-tetrahydroisoquinolines of the formula WHEREIN R1 and R2 represent hydroxy, lower alkoxy, lower alkanoyloxy or aryl-lower alkanoyl groups, R3 represents hydrogen or a lower alkyl group and R4 represents a lower alkyl, arylcarbonyl, aryl-lower alkyl, benzhydryl-lower alkyl, lower alkanoyl, aryl-lower alkanoyl, benzhydryl-lower alkanoyl or benzhydrylcarbonyl group, and acid addition salts and quaternary ammonium salts thereof, and pharmaceutical compositions containing one or more of the compounds useful for lowering blood pressure in animals.