Means and method for controlling eluent gradient in liquid chromatography

摘要

An apparatus and method for producing a gradient between two eluents. The form or slope characteristics of the gradient may be varied to suit a given application. Apparatus are provided for expanding or compressing the range of the gradient while maintaining its form over a wide range of values. In a preferred embodiment the apparatus include means for controlling the form of the reset gradient in order to avoid detrimental shock to the chromatographic column.