Theory of Liquid-Solid Adsorption Chromatography with Mixed Eluents onEnergetically Heterogeneous Adsorbents

摘要

A comprehensive theoretical description of liquid-solid adsorption chromatographyis presented for binary mobile phases. It is based on a similar approach to that used to model physical adsorption of multicomponent nonelectrolytic liquids in contact with energetically heterogeneous solids. A generalized integral equation is derived for solute retention which can be simplified by assuming ideal solution behavior for the mobile phase and that the surface heterogenity is described by a Gaussian type energy distribution. This latter simpler relationship is used to illustrate the dependence of solute retention on the energetic heterogeneity of the surface.