PROCESS FOR PREPARING NEW BU-2183 ANTIBIOTICS

摘要

A novel aminoglycoside antibiotic complex designated herein as Bu-2183 is produced by fermentation of Pseudomonas sp. strain D946-B83, A.T.C.C. 31086. Complex Bu-2183 is known to consist of at least five components, said components being herein designated Bu-2183 A, A2, B, C and D. The complex and the individual aminoglycoside components Bu-2183 A, A2, and B are found to have a broad spectrum of antibacterial activity and are especially useful in inhibiting aminoglycoside-resistant organisms including Pseudomonas species.