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process for production of mixtures of antibiotics by the cultivation of aspergillus nidulans varieta'roseus
process for production of mixtures of antibiotics by the cultivation of aspergillus nidulans varieta'roseus
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机译:曲霉曲霉培养生产抗生素混合物的方法
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摘要
A process is disclosed for preparing the A-42355 antibiotic mixture which comprises A-30912 factors A, B, D, and H, and the individual factors, A-30912 factor A, A-30912 factor B, A-30912 factor D and A-30912 factor H, which comprises cultivating the newly isolated Aspergillus nidulans var. roseus NRRL 11440 in a culture medium containing assimilable sources of carbohydrate, nitrogen, and inorganic salts under submerged aerobic fermentation conditions until a substantial amount of antibiotic activity is produced, separating the antibiotic mixture from the culture medium, and if desired, isolating the individual factors from the antibiotic mixture.
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