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TRANSFER FACTOR AND METHOD FOR PRODUCING SAME

机译:转移因子和产生转移因子的方法

摘要

Transfer Factor to be used therapeutically by parenteral administration in human beings to obtain immunity directed against an antigen which is pathogenic in man, such as cancer cells or extracts thereof, is produced by immunizing pigs or other large non-primate mammal host animals with the antigen and thereafter obtaining Transfer Factor from leukocytes from the animal. The separation of Transfer Factor from the leukocytes is performed by incubating the leukocytes and thereafter rupturing them, preferably lyophilizing the ruptured cell material, and performing dialysis to exclude molecules having a molecular weight of above 10,000.
机译:肠胃外给药的治疗因子,是通过对猪或其他大型非灵长类哺乳动物宿主动物进行免疫接种而产生的,从而获得针对人类致病性抗原(例如癌细胞或其提取物)的免疫力然后从动物的白细胞获得转移因子。通过将白细胞温育并随后使其破裂,优选冻干破裂的细胞材料,并进行渗析以排除分子量大于10,000的分子,来从白细胞中分离转移因子。

著录项

  • 公开/公告号JPS56500015A

    专利类型

  • 公开/公告日1981-01-08

    原文格式PDF

  • 申请/专利权人

    申请/专利号JP19790501929

  • 发明设计人

    申请日1979-10-24

  • 分类号A61K38/00;A61K39/00;C07K14/52;

  • 国家 JP

  • 入库时间 2022-08-22 16:22:43

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