Procedure for the obtaining of a carboxamide from the quinoxaline 1.4 dioxide. Consists of the condensation reaction of a benzofuran, substituted or not replaced, with a beta-cetoester, in the presence of a basic catalyst, such as sodium isopropylate in a polar solvent, such as isopranol anhydro, at a temperature comprised between 20 and 100gc, followed by the reaction of aminolysis with an amine, such as ethanolamine, at reflux temperature. The product is separated and purified by conventional methods. These compounds have pharmacological applications for their antibacterial activity. N (Machine-translation by Google Translate, not legally binding)
展开▼
