2,4,6-Triiodobenzonitrile derivatives and X-ray contrast media comprising them

摘要

2,4,6-Triiodobenzonitriles of the formula ##STR1## wherein Z is a direct bond or alkylene, X is --COOH or --NR.sub.1 R.sub.2 wherein R. sub. 1 is H or hydrocarbon or hydroxy-hydrocarbon and R.sub.2 is lower acyl, and Y is H or --COOH, and their simple esters, amides and pharmaceutically acceptable salts, are useful as X-ray contrast agents and can be prepared by diazotizing the corresponding 2,4,6- triiodoanilines followed by reaction with a metal cyanide.