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METHOD OF INCREASING ORAL ABSORPTION OF GLYCOSIDIC AND RELATED ANTIBIOTICS

机译:增加糖苷及相关抗生素口服吸收的方法

摘要

A drug form is provided for increasing the oral absorption of glycosidic and related antibiotics such as marcrolide, aminoglycoside, lincomycin and anthracycline antibiotics and related chemical species by the oral administration of said glycosidic and related antibiotics in a suitable pharmaceutically accepted excipient to which has been added a hydroxyaryl or hydroxyaralkyl acid or salt amide or ester thereof. The hydroxyaryl, a hydroxyaralkyl or salt amide or ester thereof is present in the drug form in quantities sufficient to be effective in enhancing the rate of oral absorption of glycosidic and related antibiotic.
机译:提供了一种药物形式,用于通过口服所述糖苷类和相关抗生素在合适的药学上可接受的赋形剂中,来增加糖苷类和相关抗生素(例如马氏内酯,氨基糖苷,林可霉素和蒽环类抗生素)和相关化学物种的口服吸收羟基芳基或羟基芳烷基酸或其盐酰胺或酯。羟基芳基,羟基芳烷基或其盐酰胺或其酯以足以有效提高糖苷和相关抗生素的口服吸收速率的量存在于药物形式中。

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