首页> 外国专利> PROCESS FOR THE PREPARATION OF NOVEL 17-SPIROSULTINES STEROID DERIVATIVES AND OF THEIR .gamma.-HYDROXY ACIDS CORRESPONDING

PROCESS FOR THE PREPARATION OF NOVEL 17-SPIROSULTINES STEROID DERIVATIVES AND OF THEIR .gamma.-HYDROXY ACIDS CORRESPONDING

机译:相应的新型17-螺氨基胍类甾醇衍生物及其γ-羟基酸的制备方法

摘要

ABSTRACT OF THE DISCLOSURE: ? To novel steroid 17-hydroxy spirosultines and the corresponding acids, answering the general formula I: (I) wherein R1 represents an alkyl radical containing 1 to 4 carbon atoms, A represents a hydrogen atom and B represents a hydrogen atom or a hydroxyl group configuration .beta., Or A and B form together a double bond, X and Y represent a group: or X represents an OH group and Y is a group: CH2-CH2 - - OM wherein M represents an alkali metal atom or an NH 4 group. The invention also provides a preparation of these novel method. The derivatives of formula (I) possess remarkable activity progrestomimétique and an anti-aldostéronique activity.
机译:公开摘要:对于新颖的类固醇17-羟基螺杂螺盐及其相应的酸,回答通式I:(I)其中R1代表含有1-4个碳原子的烷基,A代表氢原子,B代表氢原子或羟基构型β,或A和B一起形成双键,X和Y代表一个基团:或X代表一个OH基团,Y是一个基团:CH2-CH2--OM,其中M代表碱金属原子或NH 4组。本发明还提供了这些新颖方法的制剂。式(I)的衍生物具有显着的progrestomimétique活性和抗醛固酮还原活性。

著录项

  • 公开/公告号CA1121341A

    专利类型

  • 公开/公告日1982-04-06

    原文格式PDF

  • 申请/专利权人 ROUSSEL-UCLAF;

    申请/专利号CA19770289575

  • 发明设计人 TORELLI VESPERTO;PHILIBERT DANIEL;

    申请日1977-10-26

  • 分类号C07J21/00;

  • 国家 CA

  • 入库时间 2022-08-22 13:17:08

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