RETINIC ACID N-(CARBOXY)-PHENYLAMIDES AND 7,8-DEHYDRO-RETINIC ACID N-(CARBOXY)-PHENYLAMIDES, THEIR PREPARATION AND PHARMACEUTICAL FORMULATIONS CONTAINING THESE COMPOUNDS

摘要

O.Z. 0050/033446Abstract of the disclosure: all-E- and 13-Z-retinicacid compounds of the formulae I and II IIwhere the broken line is a chemical bond or two hydrogenatoms and the carboxyl group in the aromatic ring maybe in the ortho-, meta- or para-position, the preparationof these compounds, pharmaceutical formulations contain-ing these compounds, and their use as drugs in thetopical and systemic therapy and prophylaxis of pre-cancerous conditions and carcinomas, and of dermatologi-cal disorders