use of pyridinaldehyden in combating acne vulgaris

摘要

Therapeutic topical compsn. for treatment of Acne vulgaris contg. as active constituent a pyridine-aldehyde of formula (I) (where n is 0 or 1; the aldehyde is in the 2, 3 or 4 posn. and the Me gp. is in the 2 or 6 posn.). A preferred compsn. contains 0.05-5% pyridine-3-aldehyde and 5-40% ethyllactate and a diluent. The compsns. may be solns. gels, lotions, creams, ointments, or powders. The pref. active agent is pyridine-3-aldehyde at 0.05-5%. Pref. compsns. contain 5-40% ethyl lactate. Treatment is 2-3 times weekly. Improvement is evident in a few days.