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A process for the preparation of derivatives of deoxyuridine.

机译:一种制备脱氧尿苷衍生物的方法。

摘要

Compounds of formula (I): CHEM in which Y is a halogen atom, preferably a bromine atom, each of R1 and R2 is a hydrogen atom or an acyl radical of the formula X - @ - , in which X is a C1-6 alkyl group or a carboxy group of the formula HO-@-Z- in which Z is a branched- or straight-chain alkylene radical having from 1 to 4 carbon atoms in the chain, with the proviso that R1 and R2 are not simultaneously hydrogen atoms or acetyl groups; are useful in the treatment of viral infection, particularly those caused by herpes viruses.
机译:式(I)的化合物:其中R 1是R 1和R 2的Y是卤原子,优选是溴原子的,是氢原子或式X---的酰基,其中X为式HO-@-Z-的C 1-6烷基或羧基,其中Z为链中具有1-4个碳原子的支链或直链亚烷基。 R 1和R 2不同时是氢原子或乙酰基;可用于治疗病毒感染,尤其是疱疹病毒引起的感染。

著录项

  • 公开/公告号ES510611A0

    专利类型

  • 公开/公告日1983-04-16

    原文格式PDF

  • 申请/专利权人 BEECHAM GROUP PLC.;

    申请/专利号ES19820510611

  • 发明设计人

    申请日1982-03-18

  • 分类号C07H19/08;A61K31/70;

  • 国家 ES

  • 入库时间 2022-08-22 10:47:31

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