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New 4 - (4 - cinnamoyl - 1 - piperidino) butyrophenones, particularly useful as antipsychotic agents, and their method of preparation
New 4 - (4 - cinnamoyl - 1 - piperidino) butyrophenones, particularly useful as antipsychotic agents, and their method of preparation
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机译:尤其可用作抗精神病药的新型4-(4-肉桂酰基-1-哌啶子基)丁苯酮及其制备方法
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摘要
Cinnamoylpiperidinobutyrophenone derivatives and pharmaceutically acceptable salts thereof of the following general structure: IMAGE wherein R is hydrogen, alkyl, alkoxy, halogen or trifluoromethyl; and R' is hydrogen or halogen; are useful as antipsychotic agents. The novel compounds are produced by aldol condensation of a benzaldehyde with a protected 4-(4-acetyl-1-piperidino)-butyrophenone.
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