NOVEL 4- (4-CINNAMOYL-1-PIPERIDINO) BUTYROPHENONES, PARTICULARLY USEFUL AS ANTIPSYCHOTIC AGENTS, AND PROCESS FOR THE PREPARATION THEREOF

摘要

THE INVENTION CONCERNS NEW 4-CINNAMOYLPIPERIDINOBUTYROPHENONES AND THEIR SYNTHESIS INTERMEDIARIES. /P P THE COMPOUNDS OF THE INVENTION MEET THE GENERAL FORMULA: BR/ (CF DRAWING IN BOPI) BR/ IN WHICH R IS HYDROGEN, FLUOR, CHLORINE OR BROMINE AND A IS A COCH GROUP OR A CINNAMOYL GROUP OF THE FORMULA: BR/ (CF DRAWING IN BOPI) BR/ IN WHICH R IS A HYDROGEN ATOM , OF FLUOR, OF CHLORINE OR OF BROMINE OR A LOWER ALKYL, LOWER ALCOXY OR TRIFLUOROMETHYL AND Z IS EITHER A CHOSEN KETAL FUNCTION DI- (ALCOXY IN CC) AND ALKYLENEDIOXY IN CC AND CONTAINING 2 OR 3 ATOMS OF CARBON, EITHER, WHEN A IS THE CINNAMOYL GROUP AS DEFINED ABOVE, ALSO AN OXYGEN ATOM. /P P APPLICATIONS: THE COMPOUNDS IN WHICH A IS THE ABOVE CINNAMOYL GROUP AND Z IS OXYGEN AND THEIR ACID ADDITIONAL SALTS ARE ANTIPSYCHOTICS.