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METHOD AND DIALYZER FOR PRODUCING BILAYER VESICLES AND USE OF BILAYER VESICLES.
METHOD AND DIALYZER FOR PRODUCING BILAYER VESICLES AND USE OF BILAYER VESICLES.
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机译:用于生产双层囊泡的方法和透析剂以及使用双层囊泡。
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摘要
A process for producing bilayer vesicles from a colloidal solution comprising mixed micelles of a bilayer-forming substance and a detergent, comprises removing the detergent from the micelle-containing colloidal solution by means of flow-through dialysis whereby the colloidal solution is dialyzed against a dialysis liquid in a chamber whose walls are at least partially formed by a semi-permeable membrane, wherein the dialysis liquid is moved along the outer side of the semi-permeable membrane at a velocity such that the detergent concentration in the dialysis liquid, on at least 90% of the active surface of the membrane, is at most 10% of the detergent concentration in the micelle solution in contact with the other side of the membrane, and wherein a homogeneous detergent concentration is maintained in the micelle solution by the movement of the latter.
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