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Interferon inducer, a process for producing the same and pharmaceutical composition containing the same

机译:干扰素诱导剂,其制备方法和含有该诱导剂的药物组合物

摘要

A process for producing an interferon inducer by extracting a substance having interferon inducing activity with water from the tissue of a plant selected from the genus Carthamus and variants thereof containing the said active substance to give an extracted solution, forming a supernatant from the extracted solution, fractionating the supernatant to yield fractions containing a major portion of the said active substance present in the supernatant and recovering the said active substance therefrom, characterized by fractionating the supernatant to yield fractions containing the said active substance having a molecular weight of from about 10,000 to about 200,000. Preferably the seed may be used as the tissue and the fractionation may be effected by ultrafiltration using a membrane capable of fractionating substances having the above-mentioned molecular weight.
机译:一种从植物中提取具有干扰素诱导活性的物质的方法,所述物质从选自红花属及其变种的植物组织中提取具有干扰素诱导活性的物质,以得到提取液,从提取液中形成上清液,分离上清液以产生包含大部分存在于上清液中的所述活性物质的级分,并从其中回收所述活性物质,其特征在于,将上清液进行分馏以得到包含所述活性物质的分子量为约10,000至约10,000的级分。 200,000。优选地,可以将种子用作组织,并且可以使用能够分离具有上述分子量的物质的膜通过超滤来进行分离。

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