METHOD FOR CONCENTRATING IMMUNOGLOBULIN IN COW'S COLOSTRUM

摘要

PURPOSE:To concentrate efficiently the titled globulin, by defatting cow's colostrum, adding an acid to the defatted cow's colostrum to adjust the pH to a specific value, adding pepsin or rennin thereto to coagulate and separate casein, and ultrafiltering the resultant whey. CONSTITUTION:A colostrum collected within about one week after the delivery of a cow is defatted with a cream separator, and an acid, e.g. acetic or propionic acid, is added to the defatted colostrum to adjust the pH to 5.0-6.0. Pepsin or rennin is then added thereto coagulate casein. In the process, the defatted colostrum is preferably heated to 50-55 deg.C. Crud is flocculated by heating, and whey is collected. The recovered whey is then contrifuged at a low speed, and the remaining fine particles are removed. The whey is then preferably quenched to 10 deg.C or below. The resultant whey is concentrated in an ultrafiltration apparatus, e.g. plate form, etc. The resultant whey containing concentrated immunoglobulin is freeze-dried or spray-dried to give a raw material used to prepare a feed for young animals.