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Derivatives of aldohexoses, intermediates, processes for their manufacture, preparations containing such compounds, and their use

机译:醛己糖的衍生物,中间体,其制备方法,含有此类化合物的制剂及其用途

摘要

Described are derivatives of pyranoses of the formula I, manufacturing processes and intermediates, and their use as medicaments. IMAGE (I) The pyranose moiety in the compounds of the formula I is derived especially from D-glucose, but alternatively from D-galactose or D-mannose. Characteristic of the compounds of the formula I is the lower alkyl or phenyl-lower alkyl radical R8, which carries an oxycarbonyl, mercaptocarbonyl or aminocarbonyl group, which is bonded to an aliphatic, cycloaliphaticaliphatic, cycloaliphatic or aromatic hydrocarbon radical R0, each of which is optionally substituted and which may be interrupted by oxycarbonyl, mercaptocarbonyl and/or iminocarbonyl and which, like the remaining radicals of the formula I, is defined in patent claim 1.
机译:描述了式I的吡喃糖酶的衍生物,制造方法和中间体,以及它们作为药物的用途。 <图像>(I)式I的化合物中的吡喃糖部分特别衍生自D-葡萄糖,但可选地衍生自D-半乳糖或D-甘露糖。式I化合物的特征是带有氧羰基,巯基羰基或氨基羰基的低级烷基或苯基-低级烷基基团R8,该基团与脂族,脂环族脂族,脂环族或芳族烃基R0键合,每个基团为任选地被取代并且可以被氧羰基,巯基羰基和/或亚氨基羰基中断,并且与式I的其余基团一样,在专利权利要求1中定义。

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