PROCESS AND APPARATUS FOR THE REMOVAL OF WASTE METABOLITES FROM A METABOLITE-CONTAINING SOLUTION

摘要

A device for the removal of waste metabolites, especially nitrogenous poisons, from for example a hemofiltrate from a patient who suffers from uremia. The device comprises three columns (8, 9, 17), which are packed with activated carbon (10, 11 and 18), and of which two (8, 9) are parallelly coupled to each other. These two columns are adapted to be alternatingly cooled and warmed for adsorption and desorption, respectively, while the third column (17) is adapted to be permanently cooled. While one (18) of said two columns (8, 9) is cooled and throughflown by hemofiltrate for adsorption the other one (9) is exposed to warming (desorption), flushing and precooling. When said one column (8) is saturated with waste metabolites (urea) the hemofiltrate flowing is switched over so that said hemofiltrate is passed through the other, precooled column (9), whereby said first column is kept at rest and then in turn warmed, flushed and precooled. By regenerating one of the two parallelly coupled columns at the same time as the other column is used for adsorption the total treatment time for the removal of between 20 and 30 grams urea can be reduced to 3-4 hours. …??The device conveniently comprises a disposable tube set (1-6,8,9,12-14,17) interconnecting said three columns (8,9, 17) and being adapted to be attached to a patient (7). Said tube set as well as said columns are to be disposed after a whole in treatment.