首页>
外国专利>
Prolonged release pharmaceutical preparations - contg. a solid medicament e.g. nicardipine in amorphous form, polyethylene oxide and another polymer e.g. PVP
Prolonged release pharmaceutical preparations - contg. a solid medicament e.g. nicardipine in amorphous form, polyethylene oxide and another polymer e.g. PVP
展开▼
机译:缓释药物制剂-续固体药物,例如无定形尼卡地平,聚环氧乙烷和另一种聚合物,例如PVP
展开▼
页面导航
摘要
著录项
相似文献
摘要
New prolonged release pharmaceutical preparation of a solid medicament material contains the solid medicament material in amorphous form. Pref. formulations contain (a) the amorphous solid medicament material, (b) polyethylene oxide, and (c) a third component consisting of hydroxypropylmethylcellulose, hydroxypropylcellulose, methylcellulose, polyvinylpyrrolidone, carboxyvinyl polymer, hydroxypropylmethylcellulose, phthalate, cellulose acetate phthalate, methyl methacrylate/methacrylic acid copolymer, polyvinyl acetate diethylaminoacetate, dimethylaminoethyl methacrylate/methacrylic acid copolymer, 2-methyl-5-vinyl-pyridine methacrylate/methacrylic acid copolymer, citric acid, urea, succinic acid and/or amino acid. Use of the solid medicament in amorphous form avoids the loss in bioavailability often associated with formulation in prolonged release form.
展开▼