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Influenza virus vaccines, process for preparing them and process for propagating influenza viruses
Influenza virus vaccines, process for preparing them and process for propagating influenza viruses
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机译:流感病毒疫苗,其制备方法和繁殖流感病毒的方法
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摘要
1. Method of preparing an influenza virus vaccine in which cells are infected with an influenza virus and the virus multiplies in the cells, whereupon the virus is isolated and a vaccine is prepared from the isolated virus, characterized in that some of the cells of a liquid cell culture are infected with an influenza virus and the infected culture is incubated in the presence of a proteolytic enzyme the concentration of which is sufficiently high to cause growth in a multiple number of cycles without causing any detachment of cells when confluent monolayers are used as the cell culture.
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