首页>
外国专利>
Cis - platinum (ii) - complexes with diamino sugar - derivatives as ligands, process for their preparation and pharmaceutical composition containing
Cis - platinum (ii) - complexes with diamino sugar - derivatives as ligands, process for their preparation and pharmaceutical composition containing
展开▼
机译:顺式-铂(ii)-与二氨基糖形成的配合物-衍生物作为配体,其制备方法和含有
展开▼
页面导航
摘要
著录项
相似文献
摘要
The compounds have the general formula I IMAGE in which R1 is a hydrogen atom, an alkyl group with 1 to 16 carbon atoms or a protective group customary in carbohydrate chemistry, especially benzyl, tetrahydropyranyl, acetyl, halogenoacetyl, benzoyl, methanesulphonyl or para-toluenesulphonyl group, R2 and R3 are identical and are chloride, bromide or iodide or hydroxyl, nitrate, acetate, trifluoroacetate, trifluoromethanesulphonate, toluenesulphonate or perchlorate or R2 is sulphate or carbonate and R3 is H2O or R2 and R3 together are the dianion of an organic acid, especially of oxalic, malonic, hydroxymalonic, succinic, maleic, aconitic, 3,6,9-trioxaundecanedioic, 1,1- or 1,2-cyclobutanedicarboxylic, 3- or 4-carboxyphthalic or 3,4-dicarboxyphthalic acid or R2 and R3 together are a repeating anionic unit of a polymeric compound, especially dextran sulphate, chondroitin sulphate or galactan sulphate, polyglutamic acid or polyitaconic acid.
展开▼