A yeast culture containing at least 10% by weight, based on the dry cell, of S-adenosyl methionine; and a process for producing S- adenosyl methionine, which comprises cultivating a yeast having the ability to produce S-adenosyl methionine in a liquid culture medium containing methionine to accumulate at least 10% by weight, based on the dry yeast cells, of S-adenosyl methionine in the yeast cells, separating the yeast cells from the culture medium, and thereafter obtaining S- adenosyl methionine in a stable form from the yeast cells.
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