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Process for the preparation of fusion proteins and application of the thus produced fusion protein as a vaccine

机译:融合蛋白的制备方法和由此产生的融合蛋白作为疫苗的应用

摘要

A process for preparing a fused protein comprising an amino acid sequence fused to an immunogenic carrier protein, characterized by introducing a cloned or synthetic DNA segment encoding said sequence into an expression vector, wherein said DNA segment is fused to a gene encoding said immunogenic vector and allowing said host cell to express the fused protein and recovering same; a process for preparing polyclonal antibodies using the fused protein thus prepared; and the use of the fused protein as a vaccin. o
机译:一种制备包含与免疫原性载体蛋白融合的氨基酸序列的融合蛋白的方法,其特征在于将编码所述序列的克隆的或合成的DNA片段引入表达载体,其中所述DNA片段与编码所述免疫原性载体的基因融合,并且使所述宿主细胞表达融合蛋白并对其进行回收;使用由此制备的融合蛋白制备多克隆抗体的方法;以及融合蛋白作为疫苗的用途。 Ø

著录项

  • 公开/公告号DK203087A

    专利类型

  • 公开/公告日1987-10-26

    原文格式PDF

  • 申请/专利权人 KABIGEN AB;

    申请/专利号DK19870002030

  • 申请日1987-04-21

  • 分类号C12P21/02;C12P19/34;C12N15/00;C07K15/06;A61K39/395;

  • 国家 DK

  • 入库时间 2022-08-22 07:20:56

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