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difenilazometine idrossilate, loropreparazione and their use in therapy

机译:地西拉芬非那西汀,洛哌丁嗪及其在治疗中的用途

摘要

Hydroxylated diphenylazomethine of the formula (I IMAGE in which n is an integer from 1 to 4, X1, X2 and X3, which may be the same or different, each represent a hydrogen atom, a halogen atom, -OCH3 or a straight-chain or branched C1-4-alkyl group, R represents NH2, -OH or -OM/p (wherein M represents an alkali metal or alkaline earth metal of valency p) and Z represents -COOH, -COOalkyl, -CONH2, -CONHalkyl, -CON(alkyl)2, -CH2OH, -CH2Oalkyl, -Oalkyl, -NO2,- -NH2, -NHalkyl or -N(alkyl)2, each alkyl moiety having 1 to 4 carbon atoms act on the central nervous system and find use as antidepressants and anticonvulsants.
机译:式(I> )的羟基化的二苯基偶氮甲碱,其中n是1-4的整数,X1,X2和X3可以相同或不同,分别代表氢原子,卤素原子,-OCH3或直链或支链C 1-4烷基,R代表NH 2,-OH或-OM / p(其中M代表化合价为p的碱金属或碱土金属),Z代表-COOH,-COO烷基,-CONH2, -CONH烷基,-CON(烷基)2,-CH 2 OH,-CH 2 O烷基,-O烷基,-NO 2,-NH 2,-NH烷基或-N(烷基)2,每个具有1-4个碳原子的烷基部分作用于中枢神经系统,并可用作抗抑郁药和抗惊厥药。

著录项

  • 公开/公告号IT1176042B

    专利类型

  • 公开/公告日1987-08-12

    原文格式PDF

  • 申请/专利权人 SYNTHELABO S.A.;

    申请/专利号IT19840020528

  • 发明设计人 KAP@AN JEAN PIERRE;

    申请日1984-04-13

  • 分类号A61K;

  • 国家 IT

  • 入库时间 2022-08-22 07:18:16

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