New 1,4-di:hydro-pyridine-3,5 di:carboxylic acid derivs. - useful as hypotensives, vasodilators and diuretics

摘要

derivs. of general formula (I) and their salts are new, where Ar = furyl, thienyl, phenyl, pyridyl, 2,1,3-benzoxadiazolyl or 2,1,3-benzothiadiazolyl, all opt. substd. by 1 or 2 of OH, halogen, NO2, CN, CF3, 1-4C alkyl, 1-4C alkoxy, 1-4C fluoroalkoxy; 2-5C alkoxycarbonyl, 2-5C acyl, NH2 and mono- or di(1-4C alkyl)amino; R1-R3=H, 1-4C alkyl, 3-7C alkoxyalkyl, aryl, aryl(1-4C)alkyl or aryloxy(1-4C)alkyl; Ar1 and Ar2= phenyl opt. substd. by 1 or 2 of OH, halogen, 1-4C alkyl, 1-4C alkoxy, NH2, mono-or di(1-4Calkyl)amino and 1-4C fluoroalkoxy; A = 2-5C alkylene opt. substd. by 1-4C alkoxy or aryl.