NOVEL 2-(1-ALAKYLAMINOALKYL)-3-HYDROXY-1,4-NAPHTHOQUINONE, PRODUCTION THEREOF AND PRODUCTION OF 2-(1-ALKENYL)-3-HYDROXY-1,4-NAPHTHOQUINONE

摘要

NEW MATERIAL:A compound expressed by the formula (R1 is alkyl or cycloalkyl; R2 is =2C alkyl). EXAMPLE:2-(1-Methylaminobuthyl)-3-hydroxy-1,4-naphthoquinone. USE:Useful as a synthetic intermediate for 2-(1-alkenyl)-3-hydroxy-1,4- naphthoquinone and 2-alkyl-3-hydroxy-1,4-naphthoquinone which are intermediates for medicine and agricultural chemical. PREPARATION:2-Hydroxy-1,4-naphthoquinone is reacted with =3C aliphatic aldehyde in the presence of a primary amine in an inert organic solvent, preferably at =35 deg.C to provide the compound expressed by the formula. Furthermore, the compound expressed by the formula is thermally decomposed in the presence of an acid to provide the 2-(1-alkenyl)-3-hydroxy-1,4-naphthoquinone.