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PROCESS FOR PRODUCING CYCLIC AMINO-ACID DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

机译:制备环状氨基酸衍生物和包含它们的药物组合物的方法

摘要

The present invention relates to novel compounds of general formula (I), wherein R stands for hydrogen or halogen or a C1-4 alkyl or C1-4 alkoxyl group or an acylamino group containing 1 to 4 carbon atoms in the acyl moiety; X stands for one of the groups of general formulae (IV), (V) or (VI), wherein R1 means hydrogen or a straight or branched chain C1-4 alkyl group of E and/or Z configuration as well as their salts. The compounds according to the invention show cytoprotective and gastric acid secretion-inhibiting effects; their toxicity is low.
机译:本发明涉及通式(I)的新型化合物,其中R代表氢或卤素或C1-4烷基或C1-4烷氧基或在酰基部分含有1-4个碳原子的酰基氨基。 X代表通式(IV),(V)或(VI)的基团之一,其中R 1表示氢或具有E和/或Z构型的直链或支链C1-4烷基,以及他们的盐。本发明的化合物显示出细胞保护作用和胃酸分泌抑制作用。它们的毒性很低。

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