Method for the preparation of antigenic fractions used in the detection of antibodies indicative of cardiovascular trouble, antigenic fractions thus obtained and their use in the diagnosis of a cardiovascular risk

摘要

A process for the preparation of antigen fractions intended for the detection of antibodies whose presence in a certain quantity in the blood serum of a subject is correlated with the risk of a cardiovascular incident. An arterial tissue is ground, is delipidised and is treated with at least one agent taken from the group made up of an aqueous solution of an alkali metal or alkaline earth metal salt at room temperature, a warm acid, urea, guanidine and proteolytic enzymes. The invention also relates to the antigen fractions thus obtained and their use for the diagnosis of a cardiovascular risk by electrosyneresis or by an Elifa test or by an Elisa test. …IMAGE…