首页> 外国专利> method for the preparation of a drug with analgesic and ontstekingswerende operation, on the basis of 2 - aminoalkoxydibenzyletherderivaten,and method for the preparation of 2 - aminoalkoxydibenzyletherderivaten suitable for use.

method for the preparation of a drug with analgesic and ontstekingswerende operation, on the basis of 2 - aminoalkoxydibenzyletherderivaten,and method for the preparation of 2 - aminoalkoxydibenzyletherderivaten suitable for use.

机译:在2-氨基烷氧基二苄基醚衍生物的基础上制备具有止痛作用和镇痛作用的药物的方法,以及适合使用的2-氨基烷氧基二苄基醚衍生物的制备方法。

摘要

The new alkanes are of formula (I) (where X is H or halogen; R1 is 1-4C alkyl; R2 and R3 are 1-4C alkyl, or NR2R3 forms a heterocycle; n is 2 or 3). (I) and their salts are useful in steroid-free therapy of inflammatory and degenerative conditions of the osteomuscular system for relief of pain and inflammation. They have low toxicity, dosage being 100-300 mg/day, enterally or parenterally. A typical cpd. is 1-(p-chlorobenzyloxy)-1-(o-(beta(diethylamino)ethoxy)phenyl)-etha- ne.
机译:新的烷烃具有式(I)(其中X是H或卤素; R 1是1-4C烷基; R 2和R 3是1-4 C烷基,或NR 2 R 3形成杂环; n是2或3)。 (I)及其盐可用于无类固醇的骨肌肉系统炎症和退行性疾病的治疗,以减轻疼痛和炎症。它们具有低毒性,肠内或肠胃外剂量为100-300 mg / day。典型的cpd。是1-(对氯苄氧基)-1-(邻-(β(二乙氨基)乙氧基)苯基)-乙炔基。

著录项

  • 公开/公告号NL186238C

    专利类型

  • 公开/公告日1990-10-16

    原文格式PDF

  • 申请/专利号NL19760010040

  • 发明设计人

    申请日1976-09-09

  • 分类号C07C217/20;A61K31/135;C07D295/08;

  • 国家 NL

  • 入库时间 2022-08-22 06:18:23

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