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diels - alder - adducts from streptazolin and naphthochinonen and their oxidationsprodukte, processes for their manufacture and their use in the manufacture of medicinal products
diels - alder - adducts from streptazolin and naphthochinonen and their oxidationsprodukte, processes for their manufacture and their use in the manufacture of medicinal products
Streptazoline is reacted with naphthoquinones in a Diels-Alder reaction, and the adduct is then oxidized. The resulting compounds have cytotoxic activity, in particular against leukemia cells, and have an antimicrobial action and act against protozoa.
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