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A method of inducing antitumor immunocytes, and a process for producing antitumor immunocytes and antitumor immunocytes produced by the process

机译:诱导抗肿瘤免疫细胞的方法,以及产生抗肿瘤免疫细胞的方法和由该方法产生的抗肿瘤免疫细胞

摘要

A method of inducing antitumor immunocytes which is simple in operation and suitable for inducing antitumor immunocytes having not only excellent cytotoxic activity against tumor cells but also high safety, which method comprises contacting leucocytes with an insoluble, antitumor immunocyte-inducing material capable of linking with T cells, said antitumor immunocyte-inducing material comprising an insoluble carrier and a ligand linked therewith. The induced antitumor immunocytes can be simply separated in substantially ligand-free form from the insoluble, antitumor immunocyte-inducing material. The obtained antitumor immunocytes have not only excellent cytotoxic activity against tumor cells but also high safety.
机译:一种诱导抗肿瘤免疫细胞的方法,该方法操作简单并且适于诱导不仅具有对肿瘤细胞优异的细胞毒性活性而且具有高安全性的抗肿瘤免疫细胞,该方法包括使白细胞与能够与T连接的不溶性抗肿瘤免疫细胞诱导材料接触。所述抗肿瘤免疫细胞诱导材料,其包含不溶性载体和与其连接的配体。诱导的抗肿瘤免疫细胞可以简单地以基本上无配体的形式从不溶的抗肿瘤免疫细胞诱导材料中分离出来。所获得的抗肿瘤免疫细胞不仅具有优异的针对肿瘤细胞的细胞毒活性,而且具有很高的安全性。

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