Method for converting nitriles to amides and amides to nitriles

摘要

A process which comprises contacting and catalytically reacting under essentially anhydrous conditions in the liquid phase an amide with a nitrile according to the equation:RCONH₂ + R¹CN → RCN + R¹CONH₂where R and R₁ are not the same and are each selected from(1) H, hydrocarbyl, a hydrocarbyl group substituted with: one or more of F, Cl, Br, I, amido, cyano, formyl, hydrocarbylcarbonyl, hydrocarbyloxy, hydrocarbyloxycarbonyl, hydrocarbylcarbonyloxy and dihydrocarbylamino, and(2) any of group (1) where one or more H atoms are substituted by a deuterium atom.