首页> 外国专利> 19-Nor 3-keto steroids with an amine substituted 17-chain, method for their production and intermediates thereof. Their use as medicines and pharmaceutical composition containing them

19-Nor 3-keto steroids with an amine substituted 17-chain, method for their production and intermediates thereof. Their use as medicines and pharmaceutical composition containing them

机译:具有胺取代的17-链的19-Nor 3-酮类固醇,其制备方法及其中间体。它们用作药物和包含它们的药物组合物

摘要

The invention relates to the products of formula (I): …IMAGE… in which:… - R2 and R'2 = H or methyl,… - R11 = C1-18 organic radical optionally containing a hetero atom,… - R17 and R'17 represent:… either R17 = OH or acyloxy and …IMAGE… in which Z : in particular C1-5 alkylene, C2-5 alkenylene or C2-5 alkynylene, and P : pyrimidinyl or pyridyl, or …IMAGE… and R'17 = H, OH or acyloxy,… to a process for their preparation and to the intermediates in this process, to their use as medicaments and to pharmaceutical compositions containing them.
机译:本发明涉及式(I)的产物:……,其中:…-R2和R'2 = H或甲基,…-R11 = C1-18任选地含有杂原子的有机基团,…-R17和R'17代表:…R17 = OH或酰氧基和……其中Z:特别是C1-5亚烷基,C2-5亚烯基或C2-5亚炔基,P:嘧啶基或吡啶基,或... < IMAGE>…和R'17 = H,OH或酰氧基,…涉及其制备方法以及该方法中的中间体,涉及其用作药物的用途以及含有它们的药物组合物。

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