ANALOGIFREMGANGSMAADE FOR preparation of chiral 2- (2-benzyl-3-mercaptopropionyl) amino-1-ALKANOLDERIVATER or chiral 2- (2-benzyl-3-mercaptopropionyl) amino-4-METHYLTHIOSMOERSYRER or pharmaceutically acceptable cationic salts of the acids

摘要

Chiral 2-(2-benzyl-3-mercaptopropionylamino)-1-alkanol derivatives and chiral 2-(2-benzyl-3-mercaptopropionylamino)-4-methylthiobutyric acids are inhibitors of enkephalinase enzyme, reflecting their clinical utility as analgesics or anticonvulsant agents, or as therapy for disorders in which endogenous enkephalin levels are below normal.