首页> 外国专利> the timopentina similar reverse reverse to one or more strings, method for their synthesis and their use for the preparation of pharmaceutical compositions.

the timopentina similar reverse reverse to one or more strings, method for their synthesis and their use for the preparation of pharmaceutical compositions.

机译:timopentina类似的反向反向到一个或多个弦,它们的合成方法及其在制备药物组合物中的用途。

摘要

New thymopentin (TP5) analogues are disclosed which contain in their peptide chain one or more retro-inverse bonds. The new compounds have one of the following general formulas (I), (II) and (III) CHEM CHEM wherein R is hydrogen or an acyl radical, and R1 is a group of the formula -OR2 wherein R2 is a hydrogen atom or a hydrocarbon radical, and the corresponding acid or basic addition salts pharmaceutically acceptable. Such new compounds have immunostimulating activity.
机译:公开了新的胸腺五肽(TP5)类似物,其肽链中含有一个或多个逆反键。新化合物具有以下通式(I),(II)和(III)之一:[化学式] <化学式>其中R是氢或酰基,并且R 1是式-OR < 2>其中R 2是氢原子或烃基,以及相应的酸或碱加成盐是药学上可接受的。这种新化合物具有免疫刺激活性。

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