new analogues of timopentina back reversed all the links, a method for their synthesis and their use for the preparation of pharmaceutical compositions.

摘要

New thymopentin (TP5) analogues whose bonds in the peptide chain are all retro-inverted are disclosed. Such new compounds have the following general formula (I) CHEM wherein R is hydrogen or an acyl radical, and R1 is a group of the formula -OR2, wherein R2 is a hydrogen atom or a hydrocarbon radical, and the corresponding basic or acid addition salts which are pharmaceutically acceptable. The new compounds have immunostimulating activity.