4-17968/=/CGC 1470 A METHOD OF REDUCING SERUM URIC ACID AND/OR INCREASING RENAL URIC ACID CLEARANCE WITH THROMBOXANE SYNTHETASE INHIBITOR AND/OR THROMBOXANE RECEPTOR ANTAGONIST OR A COMBINATION THEREOF A method of reducing serum uric acid and/or increasing renal clearance of uric acid in a mammal in need thereof comprising administering to such mammal a uricosuric effective amount of a thromboxane synthetase inhibitor, a thromboxane receptor antagonist, or both in a combined uricosuric effective amount is disclosed. Compositions having one or more of the foregoing in combination with one or more uricosurics are also set forth and included within this invention.
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