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METHOD FOR THE DETECTION AND DETERMINATION OF ANTI- (SPOROZOA OF P. FALCIPARUM) ANTIBODIES IN HUMAN BLOOD AND DIAGNOSTIC KITS FOR CARRYING OUT THIS METHOD
METHOD FOR THE DETECTION AND DETERMINATION OF ANTI- (SPOROZOA OF P. FALCIPARUM) ANTIBODIES IN HUMAN BLOOD AND DIAGNOSTIC KITS FOR CARRYING OUT THIS METHOD
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机译:检测和测定人血和诊断试剂盒中恶性疟原虫抗原的方法
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摘要
An immunoenzimatic method is disclosed for the detection and the measurement of anti-P. falciparum sporzoite antibodies in human blood and/or in its derivatives, which operates with a synthetic antigen-enzyme conjugate capable of forming with the antisporozoite antibodies a stable antibody-synthetic antigen-enzyme complex, and one or more proteins absorbed and/or covalently linked to a solid support, which eagerly bind the antisporozoite antibody of said complex. The method, thanks to its simpleness, specificity and rapidity, is particularly useful in epidemiologic investigations into malaria and into the efficacy of an antimalarial vaccine.
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