Interferon-induced (2'-5') oligo a synthetase gene, mRNA, cDNA and enzymes having (2'-5') oligo a synthetase activity

摘要

Human DNA encoding enzymes having (2'-5') oligo A synthetase has been sequenced. The amino acid sequences of the enzymes have been deduced. Antigenic peptides have been prepared which may be used to raise antibodies which recognize and immunoprecipitate (2'-5') oligo A synthetase. Methods of monitoring interferon activity in a subject are presented.