DERIVATIVES OF GLYCERO-3(2)-PHOSPHO-L-SERINE AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM

摘要

New derivates of glycero-3(2)-phospho-L-serine having the general formula (I) wherein A is a substituted or unsubstituted (C5-C30)-alkoxy, (C5-C30)-alkenoxy, a double bound of the alkenoxy rest which does not come from the carbon atom bound to the oxygen, a halogen or a group of (II) where n is 0 or an integer 1, 2 or 3, one of the two rests B and C, which is identical to A or different from it, to one of the representations indicated for A or is a hydrogen, and the other rest respectively is the phosphatidyl-L-serine group having the formula (III) with the proviso that at least one rest A, B or C is (C5-C30)-alkoxy or (C5-C30)-alkenoxy. Also disclosed are pharmaceutically acceptable salts of compounds having the general formula (I) with bases, their process for producing them, pharmaceutical preparations containing these compounds as well as their utilization in drugs having a cytostatic activity.