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Use of 4-amino-1-(2-pyridyl)piperidines for the preparation of medicaments for the treatment and prophylaxis of conditions resulting from a dysfunction of the serotoninergic system

机译:4-氨基-1-(2-吡啶基)哌啶在制备用于治疗和预防5-羟色胺能系统功能障碍所致疾病的药物中的用途

摘要

The invention relates to the use of 4-amino-1-(2-pyridyl)piperidines of general formula (I) IMAGE in which R represents hydrogen, a halogen atom, a methyl, trifluoromethyl, (C1-C3) alkoxy, trifluoromethoxy, 2,2,2-trifluoroethoxy, (C1-C3) alkylthio or trifluoromethylthio group, or a phenoxy or phenylthio group optionally substituted with a halogen, a (C1-C3) alkyl, (C1-C3) alkoxy, (C1-C3) alkylthio or cyano group, or one of their pharmaceutically acceptable salts, for the preparation of medicaments for the treatment and prophylaxis of conditions resulting from a dysfunction of the serotoninergic system in which a selective serotoninergic action via the 5-HT3 receptors is required. IMAGE
机译:本发明涉及通式(I)的4-氨基-1-(2-吡啶基)哌啶的用途,其中R代表氢,卤素原子,甲基,三氟甲基,(C1-C3)烷氧基,三氟甲氧基,2,2,2-三氟乙氧基,(C1-C3)烷硫基或三氟甲硫基或苯氧基或苯硫基,可选地被卤素,(C1-C3)烷基,(C1-C3)烷氧基,(C1- C3)烷硫基或氰基或其药学上可接受的盐之一,用于制备用于治疗和预防由5-羟色胺能系统功能障碍引起的疾病的药物,其中需要通过5-HT3受体的选择性5-羟色胺能作用。 <图像>

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