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Use of fibronectin having a variable included type III repeat sequence as a marker for toxemia in pregnancy
Use of fibronectin having a variable included type III repeat sequence as a marker for toxemia in pregnancy
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机译:具有可变的包括的III型重复序列的纤连蛋白作为妊娠毒血症标志物的用途
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摘要
The elevation of human cellular fibronectin monomers having a variably included Type III repeat in a pregnant woman, as early as the first trimester, has been found to precede the onset of the clinical manifestations of toxemia and correlate with the severity of the disease state. The present invention provides a means of detection for and the monitoring of the toxemias of pregnancy, particularly preeclampsia and eclampsia, by the use a marker, human fibronectin having a variably included Type III repeat sequence, ED1 or ED2.
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