URETHANE-PROTECTED AMINO ACID-N-CARBOXYANHYDRIDES

摘要

1027-2ABSTRACT OF THE DISCLOSUREA urethane-protected amino acid-N-carboxyanhydride orN-thiocarboxyanhydride having the structure:wherein R and R' are hydrogen, alkyl, cycloalkyl, substituted alkylsubstituted cycloalkyl, aryl, or substituted aryl and at least one ofR and R' is other than hydrogen; R" is alkyl, aryl, substitutedalkyl or substituted aryl; Z is oxygen or sulfur; and n is 0, 1, or2. These compounds find use in polypeptide synthesis.