首页> 外国专利> CRYSTALLINE ACID ADDITION SALTS OF DIASTEREOMERICALLY PURE 1-(2,2-DIMETHYLPROPIONYLOXY)-ETHYL-3-CEPHEM-4-CARBOXYLATE

CRYSTALLINE ACID ADDITION SALTS OF DIASTEREOMERICALLY PURE 1-(2,2-DIMETHYLPROPIONYLOXY)-ETHYL-3-CEPHEM-4-CARBOXYLATE

机译:非对映体纯的1-(2,2-二甲基丙酰氧基)-乙基-3-乙炔-4-羧酸的结晶酸加成盐

摘要

The invention relates to crystalline acid addition salts of the two diastereomers of the 1-(2,2-dimethylpropionyloxy)ethyl ester of 3-cephem-4-carboxylic acid of the general formula II IMAGE in which X represents the anion of a physiologically acceptable, mono- or polybasic, inorganic or organic acid and the group =N-OH is in the syn position, pharmaceutical preparations active against bacterial infections and which contain such cephem derivatives, a process for the preparation of the cephem derivatives, and the use of the cephem derivatives for the control of bacterial infections.
机译:本发明涉及通式II 的3- Cephem-4-羧酸的1-(2,2-二甲基丙酰氧基)乙基酯的两种非对映异构体的结晶酸加成盐,其中X代表α的阴离子。生理上可接受的一元或多元碱性无机或有机酸,且基团= N-OH在同位,对细菌感染有活性的药物制剂,其中含有此类头孢烯衍生物,一种头孢烯衍生物的制备方法,以及头孢烯衍生物用于控制细菌感染的用途。

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