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NEW VARIANTS DERIVED FROM INTERFERONS OF TYPE I, PRODUCTION PROCESS THEREOF AND THEIR APPLICATIONS

机译:从I型干扰素衍生的新变种,生产过程及其应用

摘要

The invention relates to new type I interferon variants, corresponding to one of the following formulas: X1-R0 (I) or X1-X2-R0 (II) or X1-X2-X3-R0 (III) wherein X1, X2 and X3 are identical or different and each represent an amino acid and R 0 represents the amino acid sequence of the mature form of a type I interferon, a cassette allowing expression in yeast, a process for their production from yeast transformed with said cassette, and to their applications.
机译:本发明涉及新的I型干扰素变体,其对应于下式之一:X1-R0(I)或X1-X2-R0(II)或X1-X2-X3-R0(III),其中X1,X2和X3相同或不同,各自代表一个氨基酸,R 0代表I型干扰素成熟形式的氨基酸序列,允许在酵母中表达的表达盒,由所述表达盒转化的酵母生产过程及其应用程序。

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