Target specific substances, red blood cells and clot-red blood cells

摘要

The present invention provides novel components and methods for promoting platelet aggregation and controlling hemorrhage. The present invention surprisingly found that a red blood cell binds to a polypeptide comprising an RGD peptide and selectively binds to an active platelet. The recognition of a derivative red blood cell is called a thrombus-red blood cell, and it has existing blood characteristics. In the specific example, it can be seen that the thrombocytopenia specifically binds glycophorin A and B of red blood cells to the RGD peptide. The N-terminus of the Arg of RGD in the thrombo-red blood cells of the present invention is at a distance of 9-50, preferably 10-40, most preferably 11-25 A, and is spaced from the erythrocyte protein. The present invention is to replace a constituent composed of a label or reagent with a substance in a red blood cell. These are called transport-red blood cells, and these red blood cells are related to the use of target substances for transporting these substances by binding to specific tissues.