Lactobacillus kefir alcohol dehydrogenase

摘要

The present invention discloses the preparation of R- configured trialkylsilylethynyl &agr;-alcohols from similarly substituted &agr;- ketones, and vice versa, catalyzed by the alcohol dehydrogenase of Lactobacillus kefir, ATCC No. 35411. Also disclosed is the acceptance or transfer of a hydride ion from or to the pro-R face of NADPH or NADP, respectively, as catalyzed by that enzyme.